Members of the trail crew find themselves in San Francisco - where they are shanghaied and heading for New Orleans by way of South America! With Ernest Borgnine. A young Mexican who witnessed his father's brutal killing is able, via his knowledge of herbs, to help a tortured Indian - but a dark secret is revealed! A beautiful young woman is a runaway bride, and her father has posted a reward - but Flint decides to help her escape! With Rhonda Fleming. An orphan and a drifter are stowaways and must work off their passage - but is one of them a murderer? Tensions rise when an Irishman looking for a murderer raises the suspicions of other Irish immigrants on the wagon train. With Cliff Robertson. A female doctor is traveling west - and Indians threaten to attack the train unless the doctor can save a badly injured chief. A man joins the train, with a letter from a stranger who claims he can help find the man's missing brother. With Chill Wills. Ahead of the train, Flint meets an old friend who is afraid she might lose her daughter. A samurai warrior and his servant arrive carrying a large urn - which is stolen because the thieves believe it's full of gold! Flint quits the wagon train to become a lawman for frontier Tent City. With Slim Pickens. A woman rancher refuses to let the wagon train cross her land. An orphan girl is shunned by the other passengers due to her ugly disposition. Adams sends two men out to buy fresh horses - but when one of the men's horse's returns riderless to camp, trouble ensues. A single woman, shunned by the wives of the train, decides to care for an Indian baby suffering from smallpox - a conflict ensues. Flint meets up with an old enemy while passing by Fort Bridger. Two bad men abandon their plans to rob passengers when they discover gold - but winter is approaching. Flint escorts passengers to a new home in Bitter Springs - but racism causes a controversy. Screen legend Bette Davis stars as a widowed woman struggling to care for her seven children as the train moves west. The train picks up the sole survivor of an ill-fated wagon train - but the man's diary indicates he may have caused its destruction! Flint and a family find themselves lost and wandering after encountering a musical bandit. Injured while scouting a pass in snow-covered mountains, Flint finds himself with a woman who wants to trade him to the Indians! A stranger from Boston joins the train, asking suspicious questions about a newspaper editor in a nearby town. Flint escorts a woman to meet her fiance - but the man is already married! With Lorne Greene (Bonanza). Flint is lured by a Latin beauty into a trap - but later she decides to help him. Flint agrees to escort three nuns on their way west to start a school. With Vera Miles. A one-armed Quaker man faces accusations of cowardice. The crippled son of an Indian chief is captured just when the train is threatened by attack - can they trade the boy for safe passage? A mild-mannered man takes his new job as schoolteacher for the children on the train very seriously. With Wally Cox. A young woman and her father head west to try and find her missing fiancè - an artist who may be in trouble. With Angie Dickinson. An escaped convict joins the train, but a shootout with a deputy causes trouble. An injured woman finds her life on the line when a couple who offered to stay behind and help instead plan to steal her gold! Scouting for a mountain passage in a winter storm, Flint and friends take refuge in a cave - but this warm spot already has a resident, with great big teeth! A blizzard stops the train, and the Major and Flint disappear. A new wagonmaster takes over! A Spanish-Irish man who has lived with Pawnees is captured and left to die by rival Indians - when the train saves him, they are all in danger. With Robert Loggia. A preacher accidentally kills a man, and is found wandering the desert by the train. The train encounters a wandering band of Indians, who have a young man they want to hand over. A woman with four marriage-ready daughters joins the train - looking for husbands! A young woman on her way to San Francisco becomes blinded in an accident.